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Document Type |
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Article In Journal |
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Document Title |
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Helicobacter pylori infection at a university hospital in Saudi Arabia: prevalence, comparison of diagnostic modalities and endoscopic findings Helicobacter pylori infection at a university hospital in Saudi Arabia: prevalence, comparison of diagnostic modalities and endoscopic findings |
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Document Language |
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English |
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Abstract |
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The presence of Helicobacter pylori (H. pylori) was examined in 491 sequential patients, complaining mainly of epigastric pain, by three biopsy-based methods (rapid urease, histology, and culture), and by a serological test, enzyme immunosorbent assay, (ELISA). H. pylori was detected in 341 (70%) of 491 patients examined by histology, 287 (59%) by rapid urease test, whereas 385 (78%) were seropositive for H. pylori immunoglobulins by ELISA. None of the test methods used was independently sufficient to make an etiologic diagnosis of H. pylori infection. The endoscopic findings revealed that 315 (69%) of 456 patients with non-ulcer dyspepsia, 17 (74%) of 23 patients with duodenal ulcer, 7 (78%) of 9 patients with gastric ulcer, and 2 (67%) of 3 patients with gastric cancer were H. pylori positive. No statistically significant correlation was found between the endoscopic and the histopathological findings. A significant correlation was found between H. pylori infection and the histopathological gradings of gastritis (P < 0.001). |
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ISSN |
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0940-5429 |
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Journal Name |
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Indian J Pathol Microbiol. |
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Volume |
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48 |
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Issue Number |
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2 |
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Publishing Year |
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2005 AH
2005 AD |
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Article Type |
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Article |
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Added Date |
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Wednesday, March 3, 2010 |
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Researchers
| أ.د. دعـــد أكبر | Akbar, Prof. Daad | Researcher | Doctorate | |
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