Document Details Document Type : Article In Journal  Document Title : Pregnancy outcome in connective tissue diseases. نتائج ا لحمل في الأمهات المصابات بالأمراض الروماتيزم   Document Language : English  Abstract : OBJECTIVE: To describe the pregnancy outcome in women with systemic lupus erythematosus and other connective tissue diseases attending a specialized high risk clinic at the Royal London Hospital. METHODS: Retrospective review of 30 patients seen over a 30-month period. Diagnoses included 18 patients with lupus and 5 with mixed connective tissue disease. Patients were evaluated following a standardized protocol. RESULTS: For all patients there were 28 (93%) live births and 2 spontaneous abortions. Of the live births, 6 (21%) were preterms and 5 (17%) were small for gestational age. For the 18-lupus patients there were 17 (94%) live births and one spontaneous abortion. Of the live births, 3 (18%) were preterm, 25% were small for gestational age and one had neonatal lupus erythematosus. Nine patients (30%) were positive for anti Sjogren's syndrome A antibodies: 7 systemic lupus erythematosus patients (39%) and 2 mixed connective tissue disease patients. Eight patients were positive for anti-phospholipid antibodies: 5 for anti-cardiolipin and 3 patients for lupus anticoagulant. CONCLUSION: Most pregnancies complicated by lupus do well with no maternal or neonatal deaths in a multidisciplinary high-risk clinic. However a high rate of prematurity and small gestational age remains a problem  ISSN : 0930-2794  Journal Name : Saudi Med J  Volume : 7  Issue Number : 22  Publishing Year : 2001 AH 2001 AD  Article Type : Article  Added Date : Wednesday, March 10, 2010  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email جميلة قاري Kari, Jameela Researcher Doctorate   Files File Name Type Description  25875.doc doc   Back To Researches Page