Document Details

Document Type : Article In Journal 
Document Title :
Spectral Analysis of Heart Rate Variability in Diabetic Patients. A study of 20 Cases from King Abdul-Aziz University Hospital. Ann.
Spectral Analysis of Heart Rate Variability in Diabetic Patients. A study of 20 Cases from King Abdul-Aziz University Hospital. Ann.
 
Document Language : English 
Abstract : Recent advances in technology enable accurate recordings and automated analysis of 24-hour ECG for detection of beat-to-beat variability, providing not only more detailed, but much more accurate and precise information than earlier tests. Heart rate variability (HRV) decreases with age and shows a circadian variation, with maximum variability during sleep. It is also rate dependant; the heart rate shows more variability at lower heart rates. The loss of this beat-to-beat variability is a sign of disease. It has long been known that cardiovascular autonomic diabetic neuropathy (CADN) is associated with a loss of heart rate variability. These patients have a poor cardiovascular prognosis, with a 5-year mortality greater than 50%. Some of this may be attributed to microvascular or macrovascular disease. However, a more recent study has shown a relatively poor prognosis for patients with CADN in a sense of clinically detectable microvascular and macrovascular conditions. Clinically detectable autonomic failure is usually evident many years or decades after the onset of diabetes. It is likely that these patients develop subtle deficits in HRV much earlier, and these may include diminution in spectral domain analysis. Detection of such changes may be used as markers of pathology, particularly for study of the benefits of therapeutic interventions. Thus, the aim of this work was to study HRV in diabetic patients with clinical and sub-clinical autonomic neuropathy (AN), using spectral analysis, and to determine whether HRV in patients with sub-clinical AN is abnormal in comparison to normal subjects. 
ISSN : 0930-2794 
Journal Name : Annual of Saudi Medical 
Volume : 23 
Issue Number : 1 
Publishing Year : 2003 AH
2003 AD 
Article Type : Article 
Added Date : Monday, March 15, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
خضر عبدالجليلAbdel Galil, Khidir ResearcherDoctorate 

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