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Document Type |
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Thesis |
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Document Title |
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HISTOLOGICAL AND PHYSIOLOGICAL STUDIES ON THE EFFECTS OF SOME ENERGY DRINKS ON MALE RATS دراسات نسيجية وفسيولوجية عن تأثيرات بعض مشروبات الطاقة على ذكور الجرذان |
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Subject |
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Faculty of Science |
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Document Language |
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Arabic |
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Abstract |
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Consumption of Energy drinks (ED) rich in caffeine and its health problems have been increasing significantly recently between individuals. Therefore, this research aimed to study the histological effects of ED on rats’ testis, oxidative profile interfering with organ functions, and the possible reversibility of the produced effects. A total of 50 adult male rats (150-200g) were divided into five groups, these were; Group1(n =10) served as control was received water, Groups 2,3,4 and 5 (n =10 for each) received orally either Red Bull or Power Horse (3ml/kg body weight/day) for 7 weeks. Groups 4 and 5 were left for 2 weeks to recover from energy drinks treatment. Blood samples were taken for determination of serum testosterone and tissue malondialdehyde (MDA) and reduced glutathione were estimated in homogenized testes. Rat testes in ED treated groups (2,3) showed degenerated germinal epithelium with interstitial edema, dilated congested blood vessels, significantly decreased glutathione, and increased MDA levels. The mean of serum testosterone and proliferating cell nuclear antigen-positive germinal epithelium were also significantly decreased compared with the control group. However, testes of recovery groups had nearly normal histological, physiological, and immunohistochemical results. In conclusion, ED has an effect on testicular structures and functions which were recovered to almost normal when animals were allowed living without further ED. So it should be taken under restricted precautions. |
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Supervisor |
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Dr. Abdulhakim Mohammed Al Kilani |
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Thesis Type |
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Doctorate Thesis |
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Publishing Year |
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1440 AH
2018 AD |
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Added Date |
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Sunday, November 11, 2018 |
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Researchers
| فاطمة سعد العرياني | Aleryani, Fatma Saad | Researcher | Doctorate | |
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